African infectious-disease AI review finds 43 studies, uneven coverage and

Bioengineer.org

Source published: Site published:

Original article · فارسی

A systematic review found 43 studies that used artificial intelligence (AI) to predict, manage, monitor or forecast outbreaks of infectious diseases in Africa between 2015 and 2025. The studies covered diseases such as HIV, malaria, COVID-19 and tuberculosis. South Africa had the most studies, followed by Nigeria, Uganda, Ethiopia and Tanzania. This shows that research coverage varied from country to country.

The review, published in BMC Infectious Diseases, aimed to describe how AI has been used to study and manage infectious diseases across Africa and to examine the benefits and challenges of using it. It included original, peer-reviewed studies that used machine learning or deep learning to manage diseases, make predictions, monitor disease spread or predict outbreaks. The researchers followed the PRISMA 2020 guidelines and registered the review in PROSPERO under the number CRD420251243329.

The researchers searched PubMed, African Journals Online, Scopus, Google Scholar and ScienceDirect. These searches found 5,050 records: 2,551 from PubMed, 2,000 from ScienceDirect, 102 from African Journals Online, 233 from Scopus and 164 from Google Scholar. Of the 5,006 records screened, 43 met the rules set for inclusion in the review.

The researchers collected information about each study, including its main features, key findings and the measures used to show how well its AI models worked. The country breakdown showed that 10 studies came from South Africa, eight from Nigeria, six from Uganda, five from Ethiopia and four from Tanzania. These five countries had the largest numbers of studies included in the review.

The review shows that research is taking place in several parts of Africa. However, it does not show that AI research on infectious diseases is spread evenly across the continent or that the countries studied represent every country's research setting. Random forest was one of the most commonly used machine-learning models. Other commonly used models included support vector machines, artificial neural networks and logistic regression. Among deep-learning methods, long short-term memory was the most commonly used.

The measures of model performance depended on the models and results reported in each study. The review does not show that any one model consistently performed better than others across infectious-disease prediction, management, monitoring and outbreak forecasting. However, the authors concluded that AI is being used more often to address infectious diseases in Africa, although it is still not used as widely as it could be.

The researchers identified several barriers, including a lack of suitable policy frameworks, poor health-data quality, limited digital infrastructure, insufficient funding for health systems and research, and problems with governance. They called for investment and action to address these barriers. The review describes AI as a developing tool whose wider use depends on better data, infrastructure, funding and oversight. Overall, the researchers based their assessment of AI applications in African infectious-disease research on 43 studies selected from 5,050 records found through database searches.

Subject of Research: A systematic review of how artificial intelligence is used to predict, manage and monitor infectious diseases in Africa

Article Title: Use of artificial intelligence for infectious diseases in Africa: a systematic review

Article References: Anulaobi, C. C., Ogaba, A. K., Udoh, I. O., David, P. W., Ozugha, E. P., Nwadike, P. I., Maduka, Y. O., Miller, O. C., Nnana, M. E., & Ajayi, A. O. (2026). Utilization of artificial intelligence for infectious disease in Africa: a systematic review. BMC Infectious Diseases. https://doi.org/10.1186/s12879-026-14276-5

Image Credits: AI generated

DOI: 10.1186/s12879-026-14276-5

Keywords: artificial intelligence, infectious diseases, Africa, systematic review, machine learning, deep learning, public health surveillance, HIV, malaria, COVID-19, tuberculosis, Utilization

Watch video at the source ↗